That are a lot of options. It comes down to what capabilities you want it to have (# of cores, amount of RAM, PCI expansion, etc.) and how much you are willing to spend for them.
I currently have an Asus B85M-G with a 4th gen i7 and 32GB RAM. Performance is very acceptable, but I’m maxed out with the RAM and processor options.
You don’t necessarily need server hardware, though it is plentiful and cheap.
Start looking at combos in the Anniversary 2.0 “SNAFU” thread.
If the budget is smaller, the NAS Killer 4 builds are still very serviceable.